Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Landmark survival as an end-point for trials in critically ill patients – comparison of alternative durations of follow-up: an exploratory analysis. | Available online http content 13 4 R128 Research Landmark survival as an end-point for trials in critically ill patients - comparison of alternative durations of follow-up an exploratory analysis Gopal Taori1 Kwok M Ho2 3 Carol George4 Rinaldo Bellomo1 5 Steven AR Webb2 3 Graeme K Hart1 and Michael J Bailey5 department of Intensive care Austin Hospital Studley Road Melbourne 3084 Australia department of Intensive Care Royal Perth Hospital Wellington Street Perth 6001 Australia 3Clinical Associate Professor School of Population Health University of Western Australia Stirling Highway Crawley 6009 Australia 4ANZICS CORE Group Australian and New Zealand Intensive Care Society 10 levers St Carlton 3053 Australia 5ANZIC-RC School Public Health Preventive Medicine Monash University Alfred Hospital Commercial Road Melbourne 3181 Australia Corresponding author Rinaldo Bellomo Received 14 Nov 2008 Revisions requested 26 Jan 2009 Revisions received 16 Jun 2009 Accepted 4 Aug 2009 Published 4 Aug 2009 Critical Care 2009 13 R128 doi cc7988 This article is online at http content 13 4 R1 28 2009 Taori et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Interventional ICU trials have followed up patients for variable duration. However the optimal duration of follow-up for the determination of mortality endpoint in such trials is uncertain. We aimed to determine the most logical and practical mortality end-point in clinical trials of critically ill patients. Methods We performed a retrospective analysis of prospectively collected data involving 369 patients with one of the three specific diagnoses i Sepsis ii Community acquired pneumonia .
