Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: The incidence of sub-optimal sedation in the ICU: a systematic review. | Available online http content 13 6 R204 Research The incidence of sub-optimal sedation in the ICU a systematic review Daniel L Jackson1 Clare W Proudfoot2 Kimberley F Cann2 and Tim S Walsh3 1GE Healthcare Pollards Wood Nightingales Lane Chalfont St. Giles Bucks HP8 4SP UK 2Heron Evidence Development Ltd Building 210A Butterfield Technology and Business Park Luton LU2 8DL UK 3Royal Infirmary of Edinburgh 51 Little France Crescent Old Dalkeith Road Edinburgh EH16 2SA UK Corresponding author Daniel L Jackson Received 20 Jul 2009 Revisions requested 29 Sep 2009 Revisions received 1 2 Oct 2009 Accepted 16 Dec 2009 Published 16 Dec 2009 Critical Care 2009 13 R204 doi cc8212 This article is online at http content 13 6 R204 2009 Jackson et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Patients in intensive care units ICUs are generally sedated for prolonged periods. Over-sedation and undersedation both have negative effects on patient safety and resource use. We conducted a systematic review of the literature in order to establish the incidence of sub-optimal sedation both over- and under-sedation in ICUs. Methods We searched Medline Embase and CINAHL Cumulative Index to Nursing and Allied Health Literature online literature databases from 1988 to 15 May 2008 and hand-searched conferences. English-language studies set in the ICU in sedated adult humans on mechanical ventilation which reported the incidence of sub-optimal sedation were included. All abstracts were reviewed twice by two independent reviewers with all conflicts resolved by a third reviewer to check that they met the review inclusion criteria. Full papers of all included .
