Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Bedside adherence to clinical practice guidelines for enteral nutrition in critically ill patients receiving mechanical ventilation: a prospective, multi-centre, observational study. | Quenot et al. Critical Care 2010 14 R37 http content 14 2 R37 c CRITICAL CARE RESEARCH Open Access Bedside adherence to clinical practice guidelines for enteral nutrition in critically ill patients receiving mechanical ventilation a prospective multi-centre observational study Jean-Pierre Quenot1 Gaetan Plantefeve2 Jean-Luc Baudel3 Isabelle Camilatto4 Emmanuelle Bertholet5 Romain Cailliod6 Jean Reignier7 Jean-Philippe Rigaud8 Abstract Introduction The primary aim was to measure the amount of nutrients required prescribed and actually administered in critically ill patients. Secondary aims were to assess adherence to clinical practice guidelines and investigate factors leading to non-adherence. Methods Observational multicenter prospective study including 203 patients in a total of 19 intensive care units in France. The prescribed calorie supply was compared with the theoretical minimal required calorie intake 25 Kcal Kg day and with the supply actually delivered to the patient to calculate the ratio of calories prescribed required and the ratio of calories delivered prescribed. Clinical factors suspected to influence enteral nutrition were analyzed by univariate and multivariate analysis. Results The median ratio of prescribed required calories per day was 43 37-54 at day 1 and increased until day 7. From day 4 until the end of the study the median ratio was 80 . The median ratio of delivered prescribed per day was 80 for all 7 days from the start of enteral nutrition. Among the variables tested hospital type use of a local nutrition protocol sedation vasoactive drugs number of interruptions of enteral nutrition and measurement of gastric residual volume only measurement of residual volume was significant by univariate analysis. This was confirmed by multivariate analysis where gastric residual volume measurement was the only variable independently associated with the ratio of delivered prescribed calories OR 95 CI p .024 . Conclusions .
