Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Near-infrared spectroscopy during stagnant ischemia estimates central venous oxygen saturation and mixed venous oxygen saturation discrepancy in patients with severe left heart failure and additional sepsis/septic shock. | Mozina and Podbregar Critical Care 2010 14 R42 http content 14 2 R42 c CRITICAL CARE RESEARCH Open Access Near-infrared spectroscopy during stagnant ischemia estimates central venous oxygen saturation and mixed venous oxygen saturation discrepancy in patients with severe left heart failure and additional sepsis septic shock Hugo Mozina Matej Podbregar Abstract Introduction Discrepancies of 5-24 between superior vena cava oxygen saturation ScvO2 and mixed venous oxygen saturation SvO2 have been reported in patients with severe heart failure. Thenar muscle tissue oxygenation StO2 measured with near-infrared spectroscopy NIRS during arterial occlusion testing decreases slower in sepsis septic shock patients lower StO2 deoxygenation rate . The StO2 deoxygenation rate is influenced by dobutamine. The aim of this study was to determine the relationship between the StO2 deoxygenation rate and the ScvO2-SvO2 discrepancy in patients with severe left heart failure and additional sepsis septic shock treated with or without dobutamine. Methods Fifty-two patients with severe left heart failure due to primary heart disease with additional severe sepsis septic shock were included. SvO2 and ScvO2 were compared to the thenar muscle StO2 before and during arterial occlusion. Results SvO2 correlated significantly with ScvO2 Pearson correlation P however Bland Altman analysis showed a clinically important difference between both variables ScvO2-SvO2 mean 72 8 ScvO2-SvO2 difference . The ScvO2-SvO2 difference correlated with plasma lactate Pearson correlation P and the StO2 deoxygenation rate Pearson correlation P . In the group of patients treated with dobutamine the ScvO2-SvO2 difference correlated with plasma lactate Pearson correlation P and the StO2 deoxygenation rate Pearson correlation P . Conclusions In patients with severe heart failure with additional severe sepsis septic shock the ScvO2-SvO2 .
