Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Using pump for bypass surgery – on-off-on again? | Edwards and Huang Critical Care 2010 14 319 http content 14 5 319 CRITICAL CARE JOURNAL CLUB CRITIQUE L Using pump for bypass surgery - on-off-on again Jennifer H Edwards1 and David T Huang 1-2-3 University of Pittsburgh Department of Critical Care Medicine Evidence-Based Medicine Journal Club- edited by Sachin Yende Expanded abstract Citation Shroyer AL Grover FL Hattler B Collins JF McDonald GO Kozora E Lucke JC Baltz JH Novitzky D for the Veterans Affairs Randomized On Off Bypass ROOBY Study Group On-pump versus off-pump coronary artery bypass surgery. N Engl J Med 2009 361 1827-37 Background Coronary-artery bypass grafting CABG has traditionally been performed with the use of cardiopulmonary bypass on-pump CABG . CABG without cardiopulmonary bypass off-pump CABG might reduce the number of complications related to the heart-lung machine. Methods Objective To compare off-pump to on-pump CABG in terms of short- and long-term composite of complications and death from any cause as well as completeness and durability of the procedure grafting neuropsychological outcomes and use of major resources. Design Multi-center single-blind randomized controlled trial. Setting 18 Veterans Affairs medical centers 16 of which were teaching hospitals. Subjects 2203 patients who were scheduled for urgent or elective CABG-only procedures. Intervention Patients were randomized to either on- or off-pump CABG. They underwent neuropsychological testing at baseline and one year as well as follow-up angiography. Outcomes 1 Primary short-term end-point composite of death or major complications reoperation new mechanical support cardiac arrest coma stroke or renal Correspondence huangdt@ 606B Scaife Hall 3550 Terrace Street- University of Pittsburgh Pittsburgh- PA 1 5261-USA Full list of author information is available at the end of the article 2 BioMed Central 2010 BioMed Central Ltd failure requiring dialysis at discharge or day 30. 2 Primary .