Báo cáo y học: " An object simulation model for modeling hypothetical disease epidemics – EpiFlex"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài:An object simulation model for modeling hypothetical disease epidemics – EpiFlex | Theoretical Biology and Medical Modelling BioMed Central Software Open Access An object simulation model for modeling hypothetical disease epidemics - EpiFlex Brian Hanley Address BW Education and Forensics 2710 Thomes Avenue Cheyenne Wyoming 82001 USA Email Brian Hanley - bphanley@ Corresponding author Published 23 August 2006 Received 09 June 2006 Theoretical Biology and Medical Modelling 2006 3 32 doi 1742-4682-3-32 Accepted 23 August 2006 This article is available from http content 3 1 32 2006 Hanley licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background EpiFlex is a flexible easy to use computer model for a single computer intended to be operated by one user who need not be an expert. Its purpose is to study in-silico the epidemic behavior of a wide variety of diseases both known and theoretical by simulating their spread at the level of individuals contracting and infecting others. To understand the system fully this paper must be read together in conjunction with study of the software and its results. EpiFlex is evaluated using results from modeling influenza A epidemics and comparing them with a variety of field data sources and other types of modeling. EpiFlex is an object-oriented Monte Carlo system allocating entities to correspond to individuals disease vectors diseases and the locations that hosts may inhabit. EpiFlex defines eight different contact types available for a disease. Contacts occur inside locations within the model. Populations are composed of demographic groups each of which has a cycle of movement between locations. Within locations superspreading is defined by skewing of contact distributions. Results EpiFlex indicates three phenomena of interest .

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