Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài:Predicting iron and folate deficiency anaemias from standard blood testing: the mechanism and implications for clinical medicine and public health in developing countries | Theoretical Biology and Medical Modelling BioMed Central Research Open Access Predicting iron and folate deficiency anaemias from standard blood testing the mechanism and implications for clinical medicine and public health in developing countries Alan E Dugdale Address Department of Paediatrics and Child Health School of Medicine University of Queensland Q 4006 Australia Email Alan E Dugdale - Corresponding author Published 09 October 2006 Received 20 April 2006 Theoretical Biology and Medical Modelling 2006 3 34 doi 1742-4682-3-34 Accepted 09 October 2006 This article is available from http content 3 1 34 2006 Dugdale licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Developing countries have high prevalence of diseases but facilities to diagnose and treat them are limited. We must use available resources in ways not needed where there are sophisticated equipment and trained staff. Anaemia is common iron deficiency affects health and productivity folate deficiency in pregnant women causes foetal abnormalities. Few developing countries can measure serum folate or ferritin but standard automated blood analyses are widely available and can help predict folate and iron deficiency. The RDW-CV coefficient of variation of the red cell width measures the variability in the size of red blood cells RBC in routine automated analysis of blood cells but is seldom reported. Levels of RDW-CV and haemoglobin Hb can predict iron deficiency anaemia. Method and results I have written a computer model based on the standard mechanism for blood formation and destruction. This shows that before anaemia develops and during recovery there are both normal and abnormal RBC small in .
