Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Endothelial Uncalibrated pulse power analysis fails to reliably measure cardiac output in patients undergoing coronary artery bypass surgery. | Broch et al. Critical Care 2011 15 R76 http content 15 1 R76 KS CRITICAL CARE RESEARCH Open Access Uncalibrated pulse power analysis fails to reliably measure cardiac output in patients undergoing coronary artery bypass surgery 1 11 1 12 Ole Broch Jochen Renner Jan Hocker Matthias Gruenewald Patrick Meybohm Jan Schottler Markus Steinfath1 Berthold Bein1 Abstract Introduction Uncalibrated arterial pulse power analysis has been recently introduced for continuous monitoring of cardiac index CI . The aim of the present study was to compare the accuracy of arterial pulse power analysis with intermittent transpulmonary thermodilution TPTD before and after cardiopulmonary bypass CPB . Methods Forty-two patients scheduled for elective coronary surgery were studied after induction of anaesthesia before and after CPB respectively. Each patient was monitored with the pulse contour cardiac output PiCCO system a central venous line and the recently introduced LiDCO monitoring system. Haemodynamic variables included measurement of CI derived by transpulmonary thermodilution CITPTD or CI derived by pulse power analysis CIPP before and after calibration CIPPnon-cal. CIPPcal. . Percentage changes of CI ACITPTD ACIPPnon-cal. PPcal. were calculated to analyse directional changes. Results Before CPB there was no significant correlation between CIppnon-cal. and CITPTD r2 P with a percentage error PE of 86 . Higher mean arterial pressure MAP values were significantly correlated with higher CIPPnon-cal. r2 P . After CPB CIPPcal. revealed a significant correlation compared with CITPTD r2 P with PE of 28 . Changes in CIPPcal. ACIPPcal. showed a correlation with changes in CITPTD ACITPTD only after CPB r2 P . Conclusions Uncalibrated pulse power analysis was significantly influenced by MAP and was not able to reliably measure CI compared with TPTD. Calibration improved accuracy but pulse power analysis was still not consistently .