Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Species-wide distribution of highly polymorphic minisatellite markers suggests past and present genetic exchanges among house mouse subspecies. | Open Access Species-wide distribution of highly polymorphic minisatellite markers suggests past and present genetic exchanges among house mouse subspecies Frangois BonhommeH Eric Rivals Annie Orth Gemma R Grant Alec J Jeffreys and Philippe RJ Bois Addresses Biologie Integrative ISEM CNRS Université de Montpellier 2 UMR 5554 Montpellier 34095 France. tLIRMM CNRS Université de Montpellier 2 UMR 5506 rue Ada Montpellier 34392 Cedex 5 France. Department of Genetics University of Leicester Leicester LE1 7RH UK. The Scripps Research Institute Department of Cancer Biology Genome Plasticity Laboratory Parkside Drive Jupiter Florida 33458 USA. H These authors contributed equally to this work. Correspondence Frangois Bonhomme. Email bonhomme@ Published 14 May 2007 Genome Biology 2007 8 R80 doi 186 gb-2007-8-5-r80 The electronic version of this article is the complete one and can be found online at http 2007 8 5 R80 Received 12 October 2006 Revised 22 January 2007 Accepted 14 May 2007 2007 Bonhomme et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Four hypervariable minisatellite loci were scored on a panel of 116 individuals of various geographical origins representing a large part of the diversity present in house mouse subspecies. Internal structures of alleles were determined by minisatellite variant repeat mapping PCR to produce maps of intermingled patterns of variant repeats along the repeat array. To reconstruct the genealogy of these arrays of variable length the specifically designed software MS_Align was used to estimate molecular divergences graphically represented as neighbor-joining trees. Results Given the high haplotypic diversity detected mean He .
