Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: On the origin of neurons. | Meeting report On the origin of neurons Jeremy N Pulvers Judith Schenk Yoko Arai Ji-Feng Fei Kanako Saito and Wieland B Huttner Address Max Planck Institute of Molecular Cell Biology and Genetics Pfotenhauerstrasse D-01307 Dresden Germany. Correspondence Wieland B Huttner. Email huttner@ Published 31 July 2007 Genome Biology 2007 8 311 doi gb-2007-8-7-311 The electronic version of this article is the complete one and can be found online at http 2007 8 7 311 2007 BioMed Central Ltd A report on the conference Neurogenesis 2007 Tokyo Japan 15-16 May 2007. The understanding of embryonic and adult neurogenesis and their possible medical applications are highly active fields of research as became evident at the first international meeting devoted solely to mammalian brain neurogenesis entitled Neurogenesis 2007 and held at the National Museum of Emerging Science and Innovation in Tokyo this May. Exciting new insights into neurogenesis were presented and discussed encompassing many aspects of neuron generation such as progenitor cell division neuronal migration adult neurogenesis and stem-cell therapy. The dissection of these processes ranged from detailed cell biological analyses to the unraveling of transcriptional networks. Here we report a few of the highlights of the conference. Neuronal progenitors During the development of the mammalian brain neurons arise from neural stem and progenitor cells which initially proliferate by symmetric divisions and later switch to both asymmetric and symmetric neurogenic divisions. In the dorsal telencephalon of the embryo newborn neurons migrate radially to the developing six-layered cerebral cortex. Multiple types of progenitors exist with different cell biological characteristics and modes of division. To control the number type and final location of neurons the transition from proliferative to neurogenic cell divisions requires a complex network of regulation so that neural specification .
