Meta phân tích và bằng chứng y học dựa trên (EBM) xuất hiện cùng nhau như là kết quả của thực tế theo cách truyền thống học tập (ví dụ như Mô hình lịch sử "bằng chứng" được xác định bởi các cơ quan chức hàng đầu trong lĩnh vực-từ sách giáo khoa, bài tổng quan, hội thảo, và các hội nghị đồng thuận) | 174 . Glasser S. Duval treatments and addressing what criteria were used to decide that the studies analyzed were similar enough to be pooled. Evidence Based Medicine It ain t so much what we don t know that gets us into trouble as what we do know that ain t so Will Rogers http Meta-analysis and evidence based medicine EBM arose together as a result of the fact that the traditional way of learning the Historic Paradigm . evidence is determined by the leading authorities in the field-from textbooks review articles seminars and consensus conferences was based upon the assumption that experts represented infallible and comprehensive knowledge. Numerous examples of the fallibility of that paradigm are present in the literature . - Prenatal steroids for mothers to minimize risk of RDS - Treatment of eclampsia with Magnesium sulfate vs. diazepam - NTG use in suspected MI - The use of diuretics for pre-eclampsia In 1979 Cochrane stated It is surely a great criticism of our profession that we have not organised a critical summary by specialty or sub-specialty updated periodically of all relevant randomized controlled trials .20 The idea of EBM then was to devise answerable questions track down the best evidence to answer them critically appraise the validity and usefulness of the evidence apply the appraisal to clinical practice and to evaluate one s performance after applying the evidence into practice http lippub . As such EBM called for the integration of individual clinical expertise with the best available external evidence from systematic research . meta-analysis . One definition of EBM is the conscientious explicit judicious use of current best available evidence in making decisions about the care of individual patients with the use of RCTs wherever possible as the gold EBM also incorporates the need to encourage patterns of care that does more good than harm. Someone said it is not that .