Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Genetic variation in eight Chinese cattle breeds based on the analysis of microsatellite markers | Genet. Sel. Evol. 40 2008 681-692 INRA EDP Sciences 2008 DOI gse 2008027 Available online at Original article Genetic variation in eight Chinese cattle breeds based on the analysis of microsatellite markers Weibin Sun1 Hong Chen1 2 Chuzhao Lei1 Xueqin Lei3 Yinghan Zhang1 1College of Animal Science and Technology Northwest A F University Shaanxi Key Laboratory of Molecular Biology for Agriculture Yangling Shaanxi 712100 China 2Institute of Cellular and Molecular Biology Xuzhou Normal University Xuzhou Jiangsu 221116 China 3Henan Sci-tech University Luoyang Henan 471000 China Received 16 December 2007 accepted 16 May 2008 Abstract - Genetic variability and genetic relationships were investigated among eight Chinese cattle breeds using 12 microsatellite markers. Three hundred and fifty-two alleles were detected and the average number of alleles per locus ranged from in the Jiaxian breed to in the Qinchuan breed with a mean value of . The total number of alleles per microsatellite ranged from 21 INRA005 HEL1 to 40 HEL1Ĩ with a mean of per locus. The fixation indices at the 12 loci in the eight breeds were very low with a mean of . A principal components analysis and the construction of a neighborjoining tree showed that these eight Chinese cattle breeds cluster into three groups . the Yanbian and Chinese Holstein the Nanyang and Jiaxian and the four remaining breeds. This clustering agrees with the origin and geographical distributions of these Chinese breeds. Chinese cattle breed microsatellite DNA genetic variability genetic relationship 1. INTRODUCTION Since the 1980s the Chinese beef industry has expanded considerably and this progress has been accompanied by the introduction of several foreign specialized beef breeds especially from Europe. European breeds are often used as sire lines for crossbreeding with Chinese indigenous cattle breeds. Such breeding schemes have contributed in improving .