Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Purging of inbreeding depression within the Irish Holstein-Friesian population | Genetics Selection Evolution BioMed Central Research Purging of inbreeding depression within the Irish Holstein-Friesian population Sinéad Mc Parland 1 2 Francis Kearney3 and Donagh P Berry1 Address Teagasc Moorepark Dairy Production Research Centre Fermoy Co. Cork Ireland 2Animal Genomics Laboratory School of Agriculture Food Science and Veterinary Medicine and Conway Institute of Biomolecular and Biomedical Research College of Life Sciences University College Dublin Belfield Dublin 4 Ireland and 3Irish Cattle Breeding Federation Bandon Co. Cork Ireland Email Sinéad Mc Parland - Francis Kearney - fkearney@ Donagh P Berry - Corresponding author Open Access Published 21 January 2009 Received 19 January 2009 Genetics Selection Evolution 2009 41 16 doi l297-9686-4l-l6 Accepted 21 January 2009 This article is available from http content 4l l l6 2009 Mc Parland et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract The objective of this study was to investigate whether inbreeding depression in milk production or fertility performance has been partially purged due to selection within the Irish Holstein-Friesian population. Classical ancestral . the inbreeding of an individual s ancestors according to two different formulae and new inbreeding coefficients . part of the classical inbreeding coefficient that is not accounted for by ancestral inbreeding were computed for all animals. The effect of each coefficient on 305-day milk fat and protein yield as well as calving interval age at first calving and survival to second lactation was investigated. Ancestral inbreeding accounting for all common ancestors in the pedigree had a .