Báo cáo sinh học: "Prediction error variance and expected response to selection, when selection is based on the best predictor for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Prediction error variance and expected response to selection, when selection is based on the best predictor for Gaussian and threshold characters, traits following a Poisson mixed model and survival traits | 307 Genet Sei. Evol. 34 2002 307-333 INRA EDP Sciences 2002 DOI gse 2002010 Original article Prediction error variance and expected response to selection when selection is based on the best predictor -for Gaussian and threshold characters traits following a Poisson mixed model and survival traits Inge Riis Korsgaarda Anders Holst Andersenb Just Jensena a Department of Animal Breeding and Genetics Danish Institute of Agricultural Sciences . Box 50 8830 Tjele Denmark b Department of Theoretical Statistics University of Aarhus 8000 Aarhus-C Denmark Received 9 January 2001 accepted 9 February 2002 Abstract - In this paper we consider selection based on the best predictor of animal additive genetic values in Gaussian linear mixed models threshold models Poisson mixed models and log normal frailty models for survival data including models with time-dependent covariates with associated fixed or random effects . In the different models expressions are given when these can be found - otherwise unbiased estimates are given for prediction error variance accuracy of selection and expected response to selection on the additive genetic scale and on the observed scale. The expressions given for non Gaussian traits are generalisations of the well-known formulas for Gaussian traits - and reflect for Poisson mixed models and frailty models for survival data the hierarchal structure of the models. In general the ratio of the additive genetic variance to the total variance in the Gaussian part of the model heritability on the normally distributed level of the model or a generalised version of heritability plays a central role in these formulas. accuracy of selection best predictor expected response to selection heritability prediction error variance Correspondence and reprints E-mail 308 . Korsgaard et al. 1. introduction For binary threshold characters heritability has been dehned on the underlying scale liability scale and on the observed .

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