Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Making systems biology work in the 21st century. | Meeting report Making systems biology work in the 21st century Athel Cornish-Bowden Address CNRS-BIP Institut Fédératif Biologie Structurale et Microbiologie 31 chemin Joseph-Aiguier 13402 Marseille Cedex 20 France. E-mail acornish@ Published 31 March 2005 Genome Biology 2005 6 317 doi gb-2005-6-4-3l7 The electronic version of this article is the complete one and can be found online at http 2005 6 4 317 2005 BioMed Central Ltd A report on the Biochemical Society meeting Systems biology will it work Sheffield UK 5 January 2005. The idea of systems biology is not new as long ago as 1968 the mathematician and engineer Mihajlo Mesarovic regretted that in spite of considerable interest and efforts the application of systems theory in biology has not quite lived up to expectation . But what of systems biology today Does it now look more likely to lead to the expected benefits These questions are of particular urgency in the UK at a time when the Biotechnology and Biological Sciences Research Council BBSRC is planning to create six new centers for systems biology over the next two years investing 6 million in each. It was in the hope of answering them that a one-day meeting exploring the nature of systems biology and its potential was organized by the Biochemical Society early this year. In the 1950s the geneticist and biochemist Henrik Kacser was already urging biologists to take systems seriously The problem is . the investigation of systems . components related or organised in a specific way. The properties of a system are in fact more than or different from the sum of the properties of its components a fact often overlooked in zealous attempts to demonstrate additivity of certain phe-nomonena. It is with these systemic properties that we shall be mainly concerned. . To most people however systems biology is still just a combination of words they encounter with increasing frequency in the literature - a search of PubMed on 3
