Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: A compendium of Caenorhabditis elegans regulatory transcription factors: a resource for mapping transcription regulatory networks. | Research Open Access A compendium of Caenorhabditis elegans regulatory transcription factors a resource for mapping transcription regulatory networks John S Reece-HoyesH Bart DeplanckeHt Jane Shingles Christian A Grove Ian A Hope and Albertha JM WalhouC Addresses institute of Integrative and Comparative Biology Faculty of Biological Sciences School of Biology University of Leeds Woodhouse Lane Leeds LS2 9JT UK. ỶProgram in Gene Function and Expression and Program in Molecular Medicine University of Massachusetts Medical School Worcester 364 Plantation Street Lazare Research Building Room 605 MA 01605 USA. H These authors contributed equally to this work. Correspondence Albertha JM Walhout. E-mail Published 30 December 2005 Genome Biology 2005 6 Rll0 doi gb-2005-6-l3-rll0 The electronic version of this article is the complete one and can be found online at http 2005 6 l3 Rl 10 Received 26 September 2005 Revised 7 November 2005 Accepted 28 November 2005 2005 Reece-Hoyes et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Transcription regulatory networks are composed of interactions between transcription factors and their target genes. Whereas unicellular networks have been studied extensively metazoan transcription regulatory networks remain largely unexplored. Caenorhabditis elegans provides a powerful model to study such metazoan networks because its genome is completely sequenced and many functional genomic tools are available. While C. elegans gene predictions have undergone continuous refinement this is not true for the annotation of functional transcription factors. The comprehensive identification of transcription factors is essential for the
