Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: nstitute for Molecular Bioscience and ARC Centre in Bioinformatics. | Research Open Access Genome-wide review of transcriptional complexity in mouse protein kinases and phosphatases Alistair RR Forrest Darrin F Taylor Mark L Crowe Alistair M Chalk Nic J Waddell Gabriel Kolle Geoffrey J Faulkner Rimantas Kodzius Shintaro Katayama Christine Wells Chikatoshi Kai Jun Kawai Piero Carninci Yoshihide Hayashizaki and Sean M Grimmond Addresses Institute for Molecular Bioscience and ARC Centre in Bioinformatics University of Queensland Brisbane QLD 4072 Australia. Queensland Institute for Medical Research PO Royal Brisbane Hospital Brisbane QLD 4029 Australia. Center for Genomics and Bioinformatics Karolinska Institutet S-171 77 Stockholm Sweden. Genome Exploration Research Group Genome Network Project Core Group RIKEN Genomic Sciences Center GSC RIKEN Yokohama Institute Yokohama Kanagawa 230-0045 Japan. The Eskitis Institute for Cell and Molecular Therapies Griffith University QLD 4111 Australia. Genome Science Laboratory Discovery Research Institute RIKEN Wako Institute Wako Saitama 351-0198 Japan. Correspondence Alistair RR Forrest. Email Published 26 January 2006 Genome Biology 2006 7 R5 doi gb-2006-7-l-r5 The electronic version of this article is the complete one and can be found online at http 2006 7 1 R5 Received 25 August 2005 Revised 2 November 2005 Accepted l6 December 2005 2006 Forrest et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Alternative transcripts of protein kinases and protein phosphatases are known to encode peptides with altered substrate affinities subcellular localizations and activities. We undertook a systematic study to catalog the variant transcripts of every protein kinase-like and .