Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Stem cells in the genomic age. | Meeting report Stem cells in the genomic age Sally Lowell Address Centre for Development in Stem Cell Biology Institute for Stem Cell Research School of Biological Sciences University of Edinburgh West Mains Road Edinburgh EH9 3JQ UK. Email Published 22 May 2006 Genome Biology 2006 7 315 doi gb-2006-7-5-3l5 The electronic version of this article is the complete one and can be found online at http 2006 7 5 315 2006 BioMed Central Ltd A report on the 2006 Joint Spring Meeting of the British Society for Developmental Biology and the British Society for Cell Biology York UK 20-23 March 2006. Stem cells span the divide between cell biology and developmental biology and so were an especially appropriate subject for the recent joint meeting of the British Society for Developmental Biology BSDB and the British Society for Cell Biology BSCB this spring. Speakers from around the world explored this fascinating topic from a wide variety of perspectives and it was particularly interesting to see how new and emerging technologies are being used to uncover some of the mysteries of cell-fate determination. A new look at old model systems Cheryll Tickle University of Dundee UK opened the meeting by telling us that the chick which has been a model system for embryology since the time of Aristotle is now entering the genomic age. The chicken genome sequence was published a year ago and chick DNA microarrays are just now becoming available. Tickle exemplified the power of combining these new genetic tools with the more traditional strengths of the chick embryo in the analysis of the spontaneous mutant . Talpid3 protein appears to be required specifically at sites of signaling by the Sonic hedgehog Shh protein and experimental manipulation of Shh availability confirms a failure to respond properly to Shh in this mutant. Tickle outlined how Dave Burt and colleagues at the Roslin Institute have isolated the Talpid3 gene by .
