Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Enigma variations: control of sexual fate in nematode germ cells. | Minireview Enigma variations control of sexual fate in nematode germ cells Ronald E Ellis Address Department of Molecular Biology The University of Medicine and Dentistry of New Jersey B303 Science Center 2 Medical Center Drive Stratford NJ 08084 USA. Email Published 28 July 2006 Genome Biology 2006 7 227 doi gb-2006-7-7-227 The electronic version of this article is the complete one and can be found online at http 2006 7 7 227 2006 BioMed Central Ltd Abstract A new study showing that neither FEM-2 nor FEM-3 is required for spermatogenesis in Caenorhabditis briggsae unlike in Caenorhabditis elegans implies that the sex-determination pathway in these species is evolving rapidly and supports the proposal that they evolved hermaphroditism independently. Years ago French pop star Patrick Juvet raised a question that evolutionary biologists are pondering anew in the aftermath of a paper about nematode sex determination from Eric Haag David Pilgrim and their colleagues published recently in Developmental Cell 1 Où sont les femmes -Where are the fems By showing that the fem genes which are essential for spermatogenesis in Caenorhabditis elegans are dispensable in Caenorhabditis briggsae germ cells they proved that the regulatory pathways in these species have undergone recent and dramatic change. Regulation of sexual traits evolves rapidly During the 1980s and 1990s researchers cloned many of the genes that control sexual development in nematodes and fruit flies and found that none of them resembled each other reviewed in 2 . Since many other regulatory pathways were conserved these results took everyone by surprise. Later Raymond et al. 3 found that a single downstream gene mab-3 doublesex had been conserved between nematodes and insects. Taken together these data implied that the regulatory pathways that control sexual development are derived from a common ancestor but have been evolving rapidly. As an example of just how .
