Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Creating a honey bee consensus gene set. | Open Access Research Creating a honey bee consensus gene set Christine G ElsikH Aaron J Mackey Justin T Reese Natalia V Milshina David S Roos and George M Weinstock Addresses Department of Animal Science Texas A M University TAMU College Station Texas 77843 USA. Penn Genomics Institute University of Pennsylvania S. University Avenue Philadelphia Pennsylvania 19104 USA. GlaxoSmithKline S. Collegeville Road Collegeville Pennsylvania 19426 USA. Human Genome Sequencing Center Baylor College of Medicine Baylor Plaza Houston Texas 77030 USA. H These authors contributed equally to this work. Correspondence Christine G Elsik. Email c-elsik@ Published 22 January 2007 Genome Biology 2007 8 R13 doi gb-2007-8-l-rl3 The electronic version of this article is the complete one and can be found online at http 2007 8 l Rl3 Received 18 July 2006 Revised 6 October 2006 Accepted 22 January 2007 2007 Elsik et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background We wished to produce a single reference gene set for honey bee Apis mellifera . Our motivation was twofold. First we wished to obtain an improved set of gene models with increased coverage of known genes while maintaining gene model quality. Second we wished to provide a single official gene list that the research community could further utilize for consistent and comparable analyses and functional annotation. Results We created a consensus gene set for honey bee Apis mellifera using GLEAN a new algorithm that uses latent class analysis to automatically combine disparate gene prediction evidence in the absence of known genes. The consensus gene models had increased representation of honey bee genes without sacrificing quality compared .
