Báo cáo sinh học: " Recombinant adeno-associated virus type 2-mediated gene delivery into the Rpe65-/- knockout mouse eye results in limited rescue"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Recombinant adeno-associated virus type 2-mediated gene delivery into the Rpe65-/- knockout mouse eye results in limited rescue | Genetic Vaccines and Therapy BioMed Central Research Open Access Recombinant adeno-associated virus type 2-mediated gene delivery into the Rpe65- - knockout mouse eye results in limited rescue Chooi-May Lai41 Meaghan JT Yut2 Meliha Brankov2 Nigel L Barnett3 Xiaohuai Zhou4 T Michael Redmond5 Kristina Narfstrom6 and P Elizabeth Rakoczy 1 Address 1Centre for Ophthalmology and Visual Science The University of Western Australia Perth Western Australia 6009 Australia 2Department of Molecular Ophthalmology Lions Eye Institute and The University of Western Australia Perth Western Australia 6009 Australia 3Vision Touch and Hearing Research Centre School of Biomedical Sciences University of Queensland Brisbane Queensland 4072 Australia 4Virus Core Facility Gene Therapy Center University of North Carolina North Carolina 27599 USA 5Laboratory of Retinal Cell and Molecular Biology National Eye Institute National Institutes of Health Bethesda Maryland 20892 USA and 6Vision Science Group Department of Veterinary Medicine and Surgery College of Veterinary Medicine University of Missouri-Columbia Columbia Missouri 65211 USA Email Chooi-May Lai - mlai@ Meaghan JT Yu - meaghan@ Meliha Brankov - melabra@ Nigel L Barnett - Xiaohuai Zhou - xzhou@ T Michael Redmond - redmond@ Kristina Narfstrom - narfstromk@ P Elizabeth Rakoczy - rakoczy@ Corresponding author fEqual contributors Published 27 April 2004 Received 23 December 2003 Accepted 27 April 2004 Genetic Vaccines and Therapy 2004 2 3 This article is available from http content 2 1 3 2004 Lai et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Background Leber s congenital amaurosis LCA is a severe .

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