Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Prevention of airway inflammation with topical cream containing imiquimod and small interfering RNA for natriuretic peptide receptor | Genetic Vaccines and Therapy BioMed Central Research Prevention of airway inflammation with topical cream containing imiquimod and small interfering RNA for natriuretic peptide receptor Xiaoqin Wang1 2 Weidong Xu2 Subhra Mohapatra3 4 Xiaoyuan Kong2 Xu Li1 Richard F Lockey2 4 and Shyam S Mohapatra 2 4 Address 1Clinical Laboratory Center of First Affiliated Hospital Xi an Jiaotong University College of Medicine Xi an China 2Division of Allergy and Immunology Culverhouse Airway Disease and Nanomedicine Research Center University of South Florida College of Medicine Tampa Florida USA 3Endocrinology Division Internal Medicine University of South Florida College of Medicine Tampa Florida USA and 4James A. Haley VA Medical Center Tampa Florida USA Email Xiaoqin Wang - xwang1@ Weidong Xu - wxu@ Subhra Mohapatra - smohapa2@ Xiaoyuan Kong - xkong@ Xu Li - lixu@ Richard F Lockey - rlockey@ Shyam S Mohapatra - smohapat@ Corresponding author Open Access Published 15 February 2008 Received 9 October 2007 .z t-7 J n I I z 11z in Ar r 1 Accepted 15 February 2008 Genetic Vaccines and Therapy 2008 6 7 doi l479-0556-6-7 This article is available from http content 6 1 7 2008 Wang et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Asthma is a complex disease characterized by reversible airway obstruction hyperresponsiveness and chronic inflammation. Principle pharmacologic treatments for asthma include bronchodilating beta2-agonists and anti-inflammatory glucocorticosteroids but these agents do not target the main cause of the disease the generation of pathogenic Th2 cells. We previously reported .
