Báo cáo sinh học: " Enhancement of the expression of HCV core gene does not enhance core-specific immune response in DNA immunization: advantages of the heterologous DNA prime, protein boost immunization regimen"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Enhancement of the expression of HCV core gene does not enhance core-specific immune response in DNA immunization: advantages of the heterologous DNA prime, protein boost immunization regimen | Genetic Vaccines and Therapy BioMed Central Research Enhancement of the expression of HCV core gene does not enhance core-specific immune response in DNA immunization advantages of the heterologous DNA prime protein boost immunization regimen Ekaterina Alekseeva 1 Irina Sominskaya1 Dace Skrastina1 Irina Egorova2 3 Elizaveta Starodubova2 Eriks Kushners1 Marija Mihailova1 Natalia Petrakova4 Ruta Bruvere1 Tatyana Kozlovskaya1 Maria Isaguliants 2 4 5 and Paul Pumpens1 Open Access Address 1 Latvian Biomedical Research and Study Centre Ratsupites 1 Riga LV-1067 Latvia 2Swedish Institute of Infectious Disease Control SE-17182 Stockholm Sweden 3Pasteur Institute 197101 St Petersburg Russia 4Microbiology and Tumorbiology Center Karolinska Institutet 17177 Stockholm Sweden and . Ivanovsky Institute of Virology 123098 Moscow Russia Email Ekaterina Alekseeva - kate@ Irina Sominskaya - irina@ Dace Skrastina - daceskr@ Irina Egorova - egorovai69@ Elizaveta Starodubova - estarodubova@ Eriks Kushners - gaishaisrx@ Marija Mihailova - mary@ Natalia Petrakova - nvpetrakova@ Ruta Bruvere - Bruvere@ Tatyana Kozlovskaya - Tatyana@ Maria Isaguliants - Paul Pumpens - paul@ Corresponding authors Published 8 June 2009 Received 16 December 2008 Genetic Vaccines and Therapy 2009 7 7 doi 186 1479-0556-7-7 Accepted 8 June 2009 This article is available from http content 7 1 7 2009 Alekseeva et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Hepatitis C core protein is an attractive target for HCV vaccine aimed to exterminate HCV infected cells. However .

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