Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Computing inbreeding coefficients quickly B Tier University of New England, Animal Genetics and Breeding Unit Arnaidade, NSW, Australia | Genet Set Evol 1990 22 419-430 Elsevier INRA 419 Original article Computing inbreeding coefficients quickly B Tier University of New England Animal Genetics and Breeding Unit Armidale NSW Australia Received 13 June 1988 accepted 12 September 1990 Summary - An algorithm for computing inbreeding coefficients F for all animals of large populations is described. The technique relies on the subset of the numerator relationship matrix A required to compute its diagonal which contains F. A simple example illustrates that this subset is a very small part of A. inbreeding coefficients fast algorithm Resume - Calcul rapide des coefficients de consanguỉnỉté. On présente un algorithme pour calculer rapidement les coefficients de consanguinité de tous les animaux dans une grande population. La methode fait seulement intervenir le sous-ensemble de la matrice des coefficients de parenté quỉ est nécessaire au calcul de sa diagonale qui contient les coefficients de consanguinité. Un exemple simple illustre que ce sous-ensemble n est qu une petite partie de la matrice des coefficients de parenté. L algorithme est précisé sous la forme d un codage symbolique. coefficients de consanguinité calcul rapide INTRODUCTION Wright s 1922 coefficient of inbreeding F describes the probability that 2 alleles at any locus are identical by descent. Inbred offspring result from mating two animals which have one or more common ancestors. Breeders of livestock perceive inbreeding as being deleterious and consequently try to avoid mating close relatives. The relationship between prospective mates can be computed to determine the degree of inbreeding of the resulting offspring from such a mating. For inbred populations inbreeding coefficients are required to compute A 1 directly using Henderson s 1975 rules. Henderson 1976 showed the relationship between the inbreeding coefficients of an animal s parents and the contributions AGBU is a joint venture between the University of New England and NSW .
