Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. | Open Access Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes Marco van het HoogH Timothy J RastH Mikhail Martchenko Suzanne Grindle Daniel Dignard Hervé Hogues Christine Cuomo Matthew Berriman Stewart Scherer BB Magee Malcolm Whiteway Hiroji Chibana André Nantel and PT Magee Addresses Biotechnology Research Institute National Research Council of Canada Montreal Quebec H4P 2R2 Canada. University of Minnesota Minneapolis MN 55455 USA. Broad Institute of MIT and Harvard Cambridge MA USA. Wellcome Trust Sanger Institute Hinxton CB10 1SA UK. Paseo Grande Moraga CA 94556 USA. Research Center for Pathogenic Fungi and Microbial Toxicoses Chiba University Chiba 260-8673 Japan. H These authors contributed equally to this work. Correspondence PT Magee. Email magee@ Published 9 April 2007 Genome Biology 2007 8 R52 doi 186 gb-2007-8-4-r52 The electronic version of this article is the complete one and can be found online at http 2007 8 4 R52 Received 6 October 2006 Revised 28 February 2007 Accepted 9 April 2007 2007 van het Hoog et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The genomic sequence of Candida albicans the most important human fungal pathogen was published in 2004. Assembly 19 consisted of 412 supercontigs of which 266 were a haploid set since this fungus is diploid and contains an extensive degree of heterozygosity but lacks a complete sexual cycle. However sequences of specific chromosomes were not determined. Results Supercontigs from Assembly 19 183 representing of the sequence were assigned to individual chromosomes purified by pulse-field gel electrophoresis and hybridized to DNA microarrays. Nine .
