Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation. | Research Open Access The proteome of Toxoplasma gondii integration with the genome provides novel insights into gene expression and annotation Dong Xia Sanya J Sanderson Andrew R Jones Judith H Prieto John R Yates Elizabeth Bromley Fiona M Tomley Kalpana Lal Robert E Sinden Brian P Brunk David S Roos and Jonathan M Wastling Addresses Department of Pre-clinical Veterinary Science Faculty of Veterinary Science University of Liverpool Liverpool L69 7ZJ UK. Department of Cell Biology The Scripps Research Institute North Torrey Pines Road La Jolla CA 92037 USA. Division of Microbiology Institute for Animal Health Compton Berkshire RG20 7NN UK. The Division of Cell and Molecular Biology Imperial College London London SW7 2AZ UK. Department of Biology University of Pennsylvania Philadelphia PA 19104 USA. Veterinary Pathology Faculty of Veterinary Science University of Liverpool Liverpool L69 7ZJ UK. Correspondence Jonathan M Wastling. Email Published 21 July 2008 Genome Biology 2008 9 R116 doi gb-2008-9-7-r1 16 The electronic version of this article is the complete one and can be found online at http 2008 9 7 R116 Received 8 April 2008 Revised 17 June 2008 Accepted 21 July 2008 2008 Xia et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Although the genomes of many of the most important human and animal pathogens have now been sequenced our understanding of the actual proteins expressed by these genomes and how well they predict protein sequence and expression is still deficient. We have used three complementary approaches two-dimensional electrophoresis gel-liquid chromatography linked tandem mass spectrometry and MudPIT to analyze the proteome of .
