Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Current address: Genomics Division, Lawrence Berkeley National Laboratory. | Research Open Access Assaying the regulatory potential of mammalian conserved non-coding sequences in human cells Catia Attanasio Alexandre Reymond Richard Humbert Robert Lyle Michael S Kuehn Shane Neph Peter J Sabo Jeff Goldy Molly Weaver Andrew Haydock Kristin Lee Michael Dorschner Emmanouil T Dermitzakis Stylianos E Antonarakis and John A Stamatoyannopoulos Addresses Department of Genetic Medicine and Development University of Geneva Medical School 1 rue Michel Servet 1211 Geneva 4 Switzerland. Center for Integrative Genomics University of Lausanne CH-1015 Lausanne Switzerland. Department of Genome Sciences University of Washington 1705 NE Pacific Street Seattle Washington 98195 USA. Department of Medical Genetics Ullevâl University Hospital 0407 Oslo Norway. The Wellcome Trust Sanger Institute Wellcome Trust Genome Campus Hinxton Cambridge CB10 1SA UK. Current address Genomics Division Lawrence Berkeley National Laboratory 1 Cyclotron Road Berkeley CA 94720 USA. Correspondence Stylianos E Antonarakis. Email . JohnAStamatoyannopoulos. Email jstam@ Published 2 December 2008 Genome Biology 2008 9 RI68 doi gb-2008-9- 12-r 168 The electronic version of this article is the complete one and can be found online at http 2008 9 I2 RI68 Received 9 June 2008 Revised 24 September 2008 Accepted 2 December 2008 2008 Attanasio et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Conserved non-coding sequences in the human genome are approximately tenfold more abundant than known genes and have been hypothesized to mark the locations of cis-regulatory elements. However the global contribution of conserved non-coding sequences to the .
