Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Microbial co-habitation and lateral gene transfer: what transposases can tell us. | Open Access Researc h Microbial co-habitation and lateral gene transfer what transposases can tell us Sean D Hooper Konstantinos Mavromatis and Nikos C Kyrpides Address Department of Energy Joint Genome Institute DOE-JGI Genome Biology Program Mitchell Drive Walnut Creek CA 94598 USA. Correspondence Sean D Hooper. Email SHooper@ Published 24 April 2009 Received 31 December 2008 Genome Biology 2009 10 R45 doi gb-2009-10-4-r45 Revisedj Apri _200 gy g Accepted 24 April 2009 The electronic version of this article is the complete one and can be found online at http 2009 10 4 R45 2009 Hooper et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Determining the habitat range for various microbes is not a simple straightforward matter as habitats interlace microbes move between habitats and microbial communities change over time. In this study we explore an approach using the history of lateral gene transfer recorded in microbial genomes to begin to answer two key questions where have you been and who have you been with Results All currently sequenced microbial genomes were surveyed to identify pairs of taxa that share a transposase that is likely to have been acquired through lateral gene transfer. A microbial interaction network including almost 800 organisms was then derived from these connections. Although the majority of the connections are between closely related organisms with the same or overlapping habitat assignments numerous examples were found of cross-habitat and crossphylum connections. Conclusions We present a large-scale study of the distributions of transposases across phylogeny and habitat and find a significant correlation between habitat and transposase .
