Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Genome-wide analysis of mono-, di- and trimethylation of histone H3 lysine 4 in Arabidopsis thaliana. | Open Access Researc h Genome-wide analysis of mono- di- and trimethylation of histone H3 lysine 4 in Arabidopsis thaliana Xiaoyu ZhangH Yana V BernatavichuteHn Shawn Cokus Matteo Pellegrin and Steven E Jacobsen Addresses Department of Plant Biology University of Georgia Green Street Athens GA 30602 USA. Department of Molecular Cell and Developmental Biology University of California Los Angeles Charles E Young Drive South Los Angeles CA 90095 USA. Molecular Biology Institute University of California Los Angeles Charles E Young Drive South Los Angeles CA 90095 USA. Howard Hughes Medical Institute University of California Los Angeles Charles E Young Drive South Los Angeles CA 90095 USA. H These authors contributed equally to this work. Correspondence Xiaoyu Zhang. Email xiaoyu@. Steven E Jacobsen. Email Jacobsen@ Published 9 June 2009 Received 29 October 2008 Genome Biology 2009 I0 R62 doi l0. ll86 gb-2009- l0-6-r62 Rev eidj 3 r ry 2009 gy g Accepted 9 June 2009 The electronic version of this article is the complete one and can be found online at http 2009 10 6 R62 2009 Zhang et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Post-translational modifications of histones play important roles in maintaining normal transcription patterns by directly or indirectly affecting the structural properties of the chromatin. In plants methylation of histone H3 lysine 4 H3K4me is associated with genes and required for normal plant development. Results We have characterized the genome-wide distribution patterns of mono- di- and trimethylation of H3K4 H3K4mel H3K4me2 and H3K4me3 respectively in Arabidopsis thaliana seedlings using chromatin immunoprecipitation and .
