Bệnh vẩy nến khu trú (ít hơn 10% sự tham gia của BSA) có khả năng kháng với điều trị tại chỗ hoặc là vô hiệu hóa (ví dụ, palmarplantar bệnh vẩy nến) Một trong các tuýp phụ nghiêm trọng của bệnh vẩy nến địa phương | 14 Koo et al. Localized psoriasis less than 10 BSA involvement that is resistant to topical therapy or is disabling . palmarplantar psoriasis One of the serious subtypes of localized psoriasis less than 10 BSA involvement that has a possibility of progression . generalized pustular or erythrodermic psoriasis or Clinical evidence of psoriatic joint disease as assessed by the patient and physician. Part 4. Feasibility of Phototherapy Lastly the feasibility and clinical appropriateness of phototherapy is rapidly evaluated in six simple questions. Determination of Candidacy for Systemic Therapy Using the responses to the yes or no questions in Part 3 and Part 4 of the Physician Assessment the candidacy for systemic therapy is determined. If the physician has checked at least one of the shaded boxes in both Part 3 and Part 4 then the patient is a candidate for systemic therapy. BACKGROUND ON THE PQOL-12 The PQOL-12 is a valid and reliable subset of the original PQOL a 41-item self-administered disease-specific questionnaire initially developed in 1991 by John Koo . 3-5 . The questionnaire items were generated through focus groups in which patients discussed their experiences with psoriasis. A nationwide population-based demographically balanced sample of 50 000 households was then used to identify 599 psoriasis patients in the United States for item testing. The 41-item PQOL was qualitatively divided into two domains psychosocial and physical. The psychosocial domain consisted of 22 items requiring patients to characterize the impact of psoriasis on their interactions with friends and family and on their feelings and self-perception. The physical domain consisted of 19 items requesting that patients rate the impact of their psoriasis symptoms on their daily activities. PQOL items were rated on an 11-point Likert-type scale where 0 not at all 5 somewhat and 10 very much. APPLICATION OF THE ORIGINAL PQOL The 41-item PQOL was utilized in a clinical study of 71 .
