Có một tỷ lệ cao hơn của CNV trong mắt với GA lúc ban đầu có đôi mắt đồng với CNV. GA là song phương trong hơn một nửa của người dân với tình trạng này. Kích thước và tốc độ tiến triển của teo liên quan chặt chẽ giữa hai mắt của bệnh | 96 Solomon et al. months later. There is a higher incidence of CNV in eyes with GA at baseline that have fellow eyes with CNV. GA is bilateral in more than half of the people with this condition. The size and rate of progression of atrophy are highly correlated between the two eyes of patients with bilateral GA but the acuities may differ due to central sparing. Among eyes with GA with visual acuity better than 20 50 there is a 40 rate of three-line visual loss at 2 years. Maximum reading rate can be significantly affected by encroachment of GA on the fovea even while there may still be little change in visual acuity. Eyes with GA have marked loss of vision in dim environments and benefit greatly from increased lighting. The development of a preferred retinal locus PRL can aid in the effective utilization of the remaining functional retina. ACKNOWLEDGMENTS This work was supported in part by a fellowship from the Heed Foundation SDS by NEI R01 EY 08552 JSS the James S. Adams RPB Special Scholar Award JSS the Panitch Fund to Stop AMD JSS MJC and the ThyoGen Pharmaceutical Corporation JSS . REFERENCES 1. Sunness JS Schuchard R Shen N Rubin GS Dagnelie G Haselwood DM. Landmark-driven fundus perimetry using the scanning laser ophthalmoscope SLO . Invest Ophthalmol Vis Sci 1995 36 1863-1874. 2. Sarks JP Sarks SH Killingsworth MC. Evolution of geographic atrophy of the retinal pigment epithelium. Eye 1988 2 552-577. 3. Maguire P Vine AP. Geographic atrophy of the retinal pigment epithelium. Am J Ophthalmol 1986 102 621-625. 4. Schatz H McDonald HR. Atrophic macular degeneration rate of spread of geographic atrophy and visual loss. Ophthalmology 1989 96 1541-1551. 5. Sunness JS Rubin GS Applegate CA Bressler NM Marsh MJ Hawkins BS Haselwood D. Visual function abnormalities and prognosis in eyes with age-related geographic atrophy of the macula and good acuity. Ophthalmology 1997 104 1677-1691. 6. Ferris FL III Fine SL Hyman L. Age-related macular degeneration and blindness
