Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Potential benefit from using identified major gene in BLUP evaluation with truncation and optimal selection | 115 Genet. Sei. Evol. 31 1999 115-133 Inra Elsevier Paris Original article Potential benefit from using an identified major gene in BLUP evaluation with truncation and optimal selection Beatriz Villanuevaa Ricardo Pong-Wongb Brian Grundya John A. Woolliamsb a Scottish Agricultural College West Mains Road Edinburgh EH9 3JG Scotland UK b Roslin Institute Edinburgh Roslin Midlothian EH25 9PS Scotland UK Received 9 June 1998 accepted 28 January 1999 Abstract - This study investigates the benefit of including information on an identified major gene in the estimation of breeding values in BLUP selection programmes. Selection for a quantitative trait is controlled by polygenes and a major locus with known effect. The benefit of using the gene information obtained in the short-term was maintained in the long-term by applying a selection tool which makes use of BLUP evaluation and optimisation of genetic contributions for maximising genetic gain while restricting the rate of inbreeding. In the mixed inheritance model the selection tool initially proposed for an infinitesimal model was able to restrict the rate of inbreeding to the desired value and to give higher rates of response than standard truncation selection both when using and ignoring the information on the major gene. The simple use of BLUP standard truncation selection allowed long-term benefits from using the gene in situations where the favourable allele was recessive or additive with large effect. Inra Elsevier Paris major gene optimal selection I BLUP selection restricted inbreeding Resume Benefice possible de 1 utilisation d un gene majeur identifie dans une evaluation BLUP lors d une selection par troncature OU optimisée. Cette étude analyse le benefice pour la selection d inclure Finformation relative à un gène majeur identifie dans 1 estimation des valeurs génétiques par BLUP. La selection porte sur un caractère quantitatif contrôlé par des polygenes et un locus majeur Correspondence and reprints Genetics
