Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Current address: Bioinformatics Core, Mayo Clini. | Researc h Open Access Gene networks in Drosophila melanogaster integrating experimental data to predict gene function James C Costello Mehmet M Dalkilic Scott M Beason Jeff R Gehlhausen Rupali Patwardhan Sumit Middha Brian D Eads and Justen R Andrews Addresses School of Informatics Indiana University E. Tenth St Bloomington Indiana 47408 USA. Department of Biology Indiana University E. Third St Bloomington Indiana 47405 USA. Center for Genomics and Bioinformatics Indiana University E. Third St. Bloomington Indiana 47405 USA. Current address Department of Genome Sciences University of Washington NE Pacific St Seattle Washington 98195-5065 USA. Current address Bioinformatics Core Mayo Clinic First St SW Rochester Minnesota 55905 USA. Correspondence Justen R Andrews. Email jandrew@ Published 16 September 2009 Genome Biology 2009 10 R97 doi gb-2009- 10-9-r97 The electronic version of this article is the complete one and can be found online at http 2009 10 9 R97 Received 11 June 2009 Revised 1 7 August 2009 Accepted 16 September 2009 2009 Andrews et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Discovering the functions of all genes is a central goal of contemporary biomedical research. Despite considerable effort we are still far from achieving this goal in any metazoan organism. Collectively the growing body of high-throughput functional genomics data provides evidence of gene function but remains difficult to interpret. Results We constructed the first network of functional relationships for Drosophila melanogaster by integrating most of the available comprehensive sets of genetic interaction protein-protein interaction and microarray expression data. The .
