Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Runaway repeats force expansion of the Phytophthora infestans genome. | X Genome Biology Minireview Runaway repeats force expansion of the Phytophthora infestans genome Mark Gijzen Address Agriculture and Agri-Food Canada 1391 Sandford Street London Ontario N5V 4T3 Canada. Email Abstract Sequencing of the genome of the potato late blight pathogen Phytophthora infestans provides insight into genome structure and evolution within this genus of plant pathogenic oomycetes. Parasitic organisms that rely on hosts to complete their life cycles face unstable and rapidly changing selective pressures as their own reproduction affects the health and success of their host. Late blight disease of potatoes and tomatoes is caused by the plant pathogen Phytophthora infestans. The recent analysis of the P. infestans genome sequence by Haas et al. 1 has provided new answers as to how this pathogen adapts to its host and why its 240 Mb genome is unusually large among the species within its assemblage. The completion of the P. infestans genome sequence represents a milestone because of the importance of this organism to history and the study of plant disease. As every student of plant pathology knows P. infestans caused the Irish potato famine of the 1840s. The rapid spread of the disease after it was accidentally introduced to Europe from the Americas resulted in utter destruction of the potato crop. It remains the most spectacular example of a catastrophic plant disease epidemic. Anton de Bary described the life cycle of P. infestans some 140 years ago making it among the first plant pathogenic microorganisms to be well characterized. But this is not just a history lesson as P. infestans and other oomycetes continue to pose problems as plant pathogens and invasive organisms around the globe. Oomycetes are somewhat obscure fungus-like organisms that capture public attention when they destroy crops and gardens or invade new landscapes. Oomycetes are filamentous microorganisms that resemble fungi in their morphology and lifestyle. .
