Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: The missing graphical user interface for genomics. | Schatz Genome Biology 2010 11 128 http 2010 11 8 128 w Genome Biology RESEARCH HIGHLIGHT L__ The missing graphical user interface for genomics Michael C Schatz See research article http 2010 11 8 R86 Abstract The Galaxy package empowers regular users to perform rich DNA sequence analysis through a much-needed and user-friendly graphical web interface. With the advent of affordable and high-throughput DNA sequencing sequencing is becoming an essential component in nearly every genetics lab. These data are being generated to probe sequence variations to understand transcribed regulated or methylated DNA elements and to explore a host of other biological features across the tree of life and across a range of environments and conditions. Given this deluge of data novices and experts alike are facing the daunting challenge of trying to analyze the raw sequence data computationally. With so many tools available and so many assays to analyze how can one be expected to stay current with the state of the art How can one be expected to learn to use each tool and construct robust end-to-end analysis pipelines all while ensuring that input formats command-line options sequence databases and program libraries are set correctly Finally once the analysis is complete how does one ensure the results are reproducible and transparent for others to scrutinize and study In an article published in Genome Biology Jeremy Goecks Anton Nekrutenko James Taylor and the rest of the Galaxy Team Goecks etal. 1 make a great advance towards resolving these critical questions with the latest update to their Galaxy Project. The ambitious goal of Galaxy is to empower regular users to carry out their own computational analysis without having to be an expert in computational biology or computer science. Galaxy adds a desperately needed graphical user interface to genomics research making data analysis universally accessible in a web browser and .
