Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: HIV-2 diagnosis and quantification in high-risk patients. | AIDS Research and Therapy BioMed Central Open Access Case report HIV-2 diagnosis and quantification in high-risk patients Philip A Chan 1 Sarah E Wakeman1 Timothy Flanigan2 Susan Cu-Uvin2 Erna Kojic2 and Rami Kantor2 Address Department of Internal Medicine The Warren Alpert Medical School of Brown University and Rhode Island Hospital Providence RI 02903 USA and 2Division of Infectious Disease The Warren Alpert Medical School of Brown University and The Miriam Hospital Providence RI 02906 USA Email Philip A Chan - pchan@ Sarah E Wakeman - sarah_wakeman@ Timothy Flanigan - tflanigan@ Susan Cu-Uvin - susan_uvin@ Erna Kojic - ekojic@ Rami Kantor - rkantor@ Corresponding author Published 14 August 2008 Received 3 July 2008 AIDS Research and Therapy 2008 5 18 doi 1742-6405-5-18 Accepted I4 August 2008 This article is available from http content 5 1 18 2008 Chan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Current diagnostic assays for HIV-1 do not always test for the presence of HIV-2 in the United States. We present the case of a patient from Cape Verde who was admitted to our hospital with rapidly deteriorating neurological function and multiple white matter lesions on MRI likely secondary to progressive multifocal leukoencephalopathy PML . Initially the patient had a positive EIA for HIV but a negative HIV-1 Western Blot and no viral load detected on a branched-DNA assay. A repeat viral load by reverse transcriptase methodology RT-DNA detected 121 000 copies and an HIV-2 Western Blot was positive. The case highlights an extremely rare .
