Treatment outcomes and plasma level of ritonavir-boosted lopinavir monotherapy among HIV-infected patients who had NRTI and NNRTI failure | AIDS Research and Therapy BioMed Zentral Research Open Access Treatment outcomes and plasma level of ritonavir-boosted lopinavir monotherapy among HIV-infected patients who had NRTI and NNRTI failUre Weerawat Manosuthi 1 2 Sasisopin Kiertiburanakul2 Wannarat Amornnimit1 Wisit Prasithsirikul1 Supeda Thongyen1 Samruay Nilkamhang1 Kiat Ruxrungtham3 4 and Somnuek Sungkanuparph2 Address 1Bamrasnaradura Infectious Diseases Institute Ministry of Public Health Nonthaburi 11000 Thailand 2Faculty of Medicine Ramathibodi Hospital Mahidol University Bangkok Thailand 3The HIV Netherlands-Australia-Thailand HIV-NAT Research Collaboration Thai Red Cross AIDS Research Centre Bangkok Thailand and 4Department of Medicine Faculty of Medicine Chulalongkorn University Bangkok Thailand E-mail Weerawat Manosuthi - drweerawat@ Sasisopin Kiertiburanakul - sasisopin@ Wannarat Amornnimit - wannarata@ Wisit Prasithsirikul - drwisit_p@ Supeda Thongyen - supeda_t@ Samruay Nilkamhang - samruay-nil@ Kiat Ruxrungtham - rkiat@ Somnuek Sungkanuparph - ssungkanuparph@ Corresponding author Published 23 December 2009 Received 30 October 2009 AIDS Research and Therapy 2009 6 30 doi 186 1742-6405-6-30 Accepted 23 December 2009 This article is available from http content 6 1 30 2009 Manosuthi et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Different strategies of ritonavir-boosted lopinavir monotherapy have been explored however data regarding salvage therapy among HIV-infected patients who failed nucleoside reverse transcriptase inhibitor NRTI and non-nucleoside reverse transcriptase inhibitor NNRTI is still limited. Methods A .