Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Circadian rhythm dysfunction in glaucoma: A hypothesis. | Journal of Circadian Rhythms BioMed Central Review Open Access Circadian rhythm dysfunction in glaucoma A hypothesis Girardin Jean-Louis 1 2 3 4 Ferdinand Zizi1 2 3 4 Douglas R Lazzaro1 and Arthur H Wolintz1 Address Department of Ophthalmology SUNY Downstate Medical Center New York USA 2Sleep Disorders Center Department of Neurology SUNY Downstate Medical Center New York USA 3Brooklyn Research Foundation on Minority Health Kingsbrook Jewish Medical Center New York USA and 4Brooklyn Center for Health Disparities SUNY Downstate Medical Center New York USA Email Girardin Jean-Louis - gjean-louis@ Ferdinand Zizi - fzizi@ Douglas R Lazzaro - Arthur H Wolintz - Corresponding author Published 10 January 2008 Received 16 October 2007 Journal of Circadian Rhythms 2008 6 1 doi l740-339l-6-l Accepted I0 January 2008 This article is available from http content 6 l l 2008 Jean-Louis et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract The absence of circadian zeitgebers in the social environment causes circadian misalignment which is often associated with sleep disturbances. Circadian misalignment defined as a mismatch between the sleep-wake cycle and the timing of the circadian system can occur either because of inadequate exposure to the light-dark cycle the most important synchronizer of the circadian system or reduction in light transmission resulting from ophthalmic diseases . senile miosis cataract diabetic retinopathy macular degeneration retinitis pigmentosa and glaucoma . We propose that glaucoma may be the primary ocular disease that directly compromises photic input to the circadian time-keeping system .
