Báo cáo y học: "Aortitis requiring aortic repair associated with glaucoma, thyroiditis, glaucoma, and neuropathy: case"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Aortitis requiring aortic repair associated with glaucoma, thyroiditis, glaucoma, and neuropathy: case | Stõllberger et al. Journal of Cardiothoracic Surgery 2011 6 74 http content 6 1 74 JCTS JOURNAL OF CARDIOTHORACIC SURGERY CASE REPORT Open Access Aortitis requiring aortic repair associated with glaucoma thyroiditis glaucoma and neuropathy case report 1 1 1 2 3 4 Claudia Stollberger Marion Avanzini Aileen Hanafin Ramona Sanani Georg Wieselthaler Nikolaus Wick Gunther Bayer4 Gunther Molzer5 and Josef Finsterer6 Abstract Aortitis may be due to infectious and non-infectious causes. We observed aortitis associated with glaucoma thyroiditis pericarditis pleural effusion and neuropathy in a 63-years old woman. Despite antibiotic therapy inflammatory signs persisted and resolved only after initiation of glucocorticoid therapy. Increasing aortic ectasia necessitated resection of the ascending aorta and implantation of a Vascutek 30 mm prosthesis. Histologically a granulomatous aortitis was diagnosed. Since all other possible causes were excluded an immunological mechanism of the aortitis is suspected and possible triggering factors are discussed. Background Aortitis of the ascending aorta may be due to infectious and non-infectious causes comprising several systemic disorders 1 2 . Aortitis associated with glaucoma thyroiditis pericarditis pleural effusion and neuropathy with prompt clinical response to glucocorticoids has not been described so far. Case presentation A 63-year old HIV-negative Iranian female was hospitalized in May 2004 because of fatigue undulating fever night sweats and weight loss starting 8 weeks before. In 1991 and 1992 she had undergone bilateral iridectomy because of glaucoma. She has had 2 uneventful pregnancies and wan through menopause at the age of 52. Twenty-seven years ago an intrauterine device IUD had been implanted but never been removed. She smoked 20 cigarettes day. Physical examination was normal the blood-pressure was 130 75 mmHg bilaterally. Blood tests showed normochromic anaemia haemoglobin g dl .

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