Báo cáo y học: "Totally biological composite aortic stentless valved conduit for aortic root replacement: 10-year experience"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Totally biological composite aortic stentless valved conduit for aortic root replacement: 10-year experience. | Galinanes et al. Journal of Cardiothoracic Surgery 2011 6 86 http content 6 1 86 JCTS JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Totally biological composite aortic stentless valved conduit for aortic root replacement 10-year experience Manuel Galinanes1 2 Ayo Meduoye1 Ignacio Ferreira3 and Andrzej Sosnowski1 Abstract Objectives To retrospectively analyze the clinical outcome of a totally biological composite stentless aortic valved conduit No-React BioConduit implanted using the Bentall procedure over ten years in a single centre. Methods Between 27 10 99 and 19 01 08 the No-React BioConduit composite graft was implanted in 67 patients. Data on these patients were collected from the in-hospital database from patient notes and from questionnaires. A cohort of patients had 2D-echocardiogram with an average of years post-operatively to evaluate valve function calcification and the diameter of the conduit. Results Implantation in 67 patients represented a follow-up of patient-year. Males were 60 of the operated population with a mean age of years range years 21 of them below the age of 65. After a mean follow-up of years range of years more than 50 of the survivors were in NYHA I II and more than 60 of the survivors were angina-free CCS 0 . The overall 10-year survival following replacement of the aortic valve and root was 51 . During this period 88 of patients were free from valved-conduit related complications leading to mortality. Post-operative echocardiography studies showed no evidence of stenosis dilatation calcification or thrombosis. Importantly during the 10-year follow-up period no failures of the valved conduit were reported suggesting that the tissue of the conduit does not structurally change histology of one explant showed normal cusp and conduit . Conclusions The No-React BioConduit composite stentless aortic valved conduit provides excellent long-term

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