Báo cáo y học: "Neurturin enhances the recovery of erectile function following bilateral cavernous nerve crush injury in the rat"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Neurturin enhances the recovery of erectile function following bilateral cavernous nerve crush injury in the rat. | Journal of Brachial Plexus and Peripheral Nerve Injury BioMed Central Research article Neurturin enhances the recovery of erectile function following bilateral cavernous nerve crush injury in the rat Anthony J Bella 1 Thomas M Fandel1 Kavirach Tantiwongse1 William O Brant1 Robert D Klein2 Carlos A Garcia2 and Tom F Lue11 Open Access Address 1Knuppe Molecular Urology Laboratory and Department of Urology University of California San Francisco USA and 2Rinat Neuroscience South San Francisco USA Email Anthony J Bella - abella@ Thomas M Fandel - tfandel@ Kavirach Tantiwongse - kavirach@ William O Brant - willbrant@ Robert D Klein - robertklein@ Carlos A Garcia - Tom F Lue - tlue@ Corresponding author fEqual contributors Published 6 March 2007 Received 10 October 2006 Journal of Brachial Plexus and Peripheral Nerve Injury 2007 2 5 doi 86 1749-7221 -2- Accepted 6 March 2007 5 This article is available from http content 2 1 5 2007 Bella et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The molecular mechanisms responsible for the survival and preservation of function for adult parasympathetic ganglion neurons following injury remain incompletely understood. However advances in the neurobiology of growth factors neural development and prevention of cell death have led to a surge of clinical interest for protective and regenerative neuromodulatory strategies as surgical therapies for prostate bladder and colorectal cancers often result in neuronal axotomy and debilitating loss of sexual function or continence. In vitro studies have identified neurturin a glial cell line-derived neurotrophic .

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