Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Daptomycin as a possible new treatment option for surgical management of Methicillin-Resistant Staphylococcus aureus sternal wound infection after cardiac surgery. | Popov et al. Journal of Cardiothoracic Surgery 2010 5 57 http content 5 1 57 JOTS JOURNAL OF CARDIOTHORACIC SURGERY CASE REPORT Open Access Daptomycin as a possible new treatment option for surgical management of Methicillin-Resistant Staphylococcus aureus sternal wound infection after cardiac surgery 1 t t 1 1 1 2 Aron F Popov Jan D Schmitto Theodor Tirilomis Christian Bireta Kasim O Coskun Suyog A Mokashi Alexander Emmert1 Martin Friedrich1 Christoph H Wiese3 Friedrich A Schoendube1 Abstract We present a case of a 77-year old female who had undergone a coronary artery bypass grafting with an aortic valve replacement and developed three month later a Methicillin-Resistant Staphylococcus aureus MRSA sternal wound infection which was successful treated with Daptomycin combined with vacuum-assisted closure VAC . Introduction Sternal wound infection is a severe complication in cardiac surgery despite continuing efforts to improve perioperative conditions. This complication is often associated with significant morbidity and mortality rates of up to 45 1 with prolonged hospitalization 2 and additional surgical procedures as well as prolonged antibiotic therapy and its inherent high costs 3 . The most common conventional treatments involve surgical revision open dressing closed mediastinal irrigation debridement complete sternectomy or reconstruction with omental or muscleflaps 4 . With the increase of MRSA infection the accompanying antibiotic therapy has received more attention for treatment of sternal wound infections after cardiac surgery. Case Report A 77-year-old female was admitted with coronary artery disease and severe aortic stenosis to the Department of Cardiac Surgery of the University Hospital of Goettingen Germany in July of 2007. A coronary artery bypass grafting left anterior descending artery was revascularized by the left internal mammarian artery and an aortic valve replacement Cryolife O Brien 23 mm Correspondence .
