Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Intrapleural instillation of autologous blood for persistent air leak in spontaneous pneumothoraxis it as effective as it is safe? | Karangelis et al. Journal of Cardiothoracic Surgery 2010 5 61 http content 5 1 61 JOTS JOURNAL OF CARDIOTHORACIC SURGERY STUDY PROTOCOL Open Access Intrapleural instillation of autologous blood for persistent air leak in spontaneous pneumothorax-is it as effective as it is safe Dimos Karangelis Georgios I Tagarakis Marios Daskalopoulos Georgios Skoumis Nicholaos Desimonas Vasileios Saleptsis Theocharis Koufakis Athanasios Drakos Dimitrios Papadopoulos Nikolaos B Tsilimingas Abstract Objective The aim of the present study was to evaluate the efficacy of autologous blood pleurodesis in the management of persistent air leak in spontaneous pneumothorax. Patients and methods A number of 15 patients 10 male and 5 female were included in this prospective study between March 2005 and December 2009. The duration of the air leak exceeded 7 days in all patients. The application of blood pleurodesis was used as the last preoperative conservative method of treatment in 12 patients. One patient refused surgery and two were ineligible for operation due to their comorbidities. A blood sample of 50 ml was obtained from the patient s femoral vein and immediately introduced into the chest tube. Results A success rate of 27 was observed having the air leak sealed in 4 patients in less than 24 hours. Conclusion Despite our disappointingly poor outcome the authors believe that the procedure s safety convenience and low cost establish it as a worth trying method of conservative treatment for patients with the aforementioned pathology for whom no other alternative than surgery would be a choice. Introduction Persistent air leak is frequently encountered in thoracic surgery especially after pulmonary surgery or pneumothorax. It prolongs patient s hospital stay and is considered to be a difficult problem regarding its management 1 2 . Pleurodesis is an excellent method used to treat air leak and it is feasible by means of surgery autologous blood and several .
