Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Is distortion of the bioprosthesis ring a risk factor for early calcification? | Cereijo et al. Journal of Cardiothoracic Surgery 2010 5 77 http content 5 1 77 JOTS JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Is distortion of the bioprosthesis ring a risk factor for early calcification Jose Manuel Martinez Cereijo1 Jose Rubio Alvarez1 Juan Sierra Quiroga1 Anxo Martinez de Alegria2 Jose Manuel Suarez Penaranda3 Abstract Background As the population ages bioprosthesis are increasingly being used in cardiac valve replacement. Pericardial bioprosthesis combine an excellent hemodynamic performance with low thrombogenicity but valve failure associated with calcification remains a concern with these valves. We describe distortion of the bioprosthesis ring as a risk factor for early calcification. Methods A total of 510 patients over the age of 70 years underwent isolated aortic valve replacement with the Mitroflow A12 pericardial bioprosthesis. Thirty two patients 6 2 have undergone a second aortic valve replacement due to structural valve dysfunction resulting from valve calcification. In all patients a chest radiography and coronary angiography was performed before reoperation. A 64 Multidetector Computed Tomography MDCT with retrospective ECG gating study was performed in four patients to evaluate the aortic bioprosthesis. Results Chest radiography showed in all patients an irregular bioprosthesis ring. At preoperative coronary angiography a distorted bioprosthesis ring was detected in all patients. Macroscopic findings of the explanted bioprostheses included extensive calcification in all specimens. Conclusion There was a possible relationship between early bioprosthetic calcification and radiologic distortion of the bioprosthesis ring. As the population ages bioprosthesis are increasingly being used in cardiac valve replacement. Pericardial bioprosthesis combine an excellent hemodynamic performance 1 with low thrombogenicity 2 but valve failure associated with calcification remains a concern with .
