Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Isolated cardiophrenic angle node metastasis from ovarian primary. report of two cases. | Ragusa et al. Journal of Cardiothoracic Surgery 2011 6 1 http content 6 1 1 JCTS JOURNAL OF CARDIOTHORACIC SURGERY CASE REPORT Open Access Isolated cardiophrenic angle node metastasis from ovarian primary. report of two cases 1 1 I-X z- 1 1 2 1 Mark Ragusa Jacopo Vannucci Rosanna Capozzi Niccolò Daddi Nicola Avenia Francesco Puma Abstract Ovarian cancer is the most lethal gynaecologic malignancy. It usually spreads out of the abdomen involving thoraco-abdominal organs and serosal surface. This disease is poorly curable and surgery at early stage is supposed to achieve the best survival outcome. In systemic dissemination chemiotherapy is indicated sometimes with neoadjuvant aim. The most common clinical expressions of advanced ovarian carcinoma are multiple adenopathy neoplastic pleuritis peritoneal seeding and distant metastasis mainly hepatic and pulmonary. Isolated adenopathy of the mediastinum is rare and isolated bilateral have never been described before. We report two cases of isolated bilateral cardiophrenic angle lymphnode metastasis from ovarian carcinoma without peritoneal and pleural involvement. Both patients were successfully resected through minimally invasive thoracic surgery. About the role of surgery few data are available but survival seems to be longer after resection thus more investigation is required to make the indication to surgery more appropriate in advanced cases. Background The cardiophrenic angle lymphnodes CPLN were classified by Rouviere into two groups anterior prepericardiac and middle latero-pericardiac. The afferent lymphatics of CPLN drain areas from the diaphragm liver pleura and anterior abdominal wall and they empty into the internal mammary chain. Malignant lymphoma and metastases of abdominal or thoracic neoplasms have been mentioned to be possible causes of CPLN enlargement. Most of the times the disease is unilateral. CPLN involvement may represent a staging and prognostic indicator for .
