Báo cáo y học: "AP-43 expression correlates with spinal motoneuron regeneration following root avulsion"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: AP-43 expression correlates with spinal motoneuron regeneration following root avulsion. | Journal of Brachial Plexus and Peripheral Nerve Injury BioMed Central Research article GAP-43 expression correlates with spinal motoneuron regeneration following root avulsion Qiuju Yuan1 4 Bing Hu1 Huanxing Su1 Kwok-Fai So1 2 5 Zhixiu Lin4 and Wutian Wu 1 2 3 5 Address Department of Anatomy Li Ka Shing Faculty of Medicine The University of Hong Kong Pokfulam Hong Kong SAR China 2State Key Laboratory of Brain and Cognitive Sciences The University of Hong Kong Pokfulam Hong Kong SAR China 3Research Center of Reproduction Development and Growth Li Ka Shing Faculty of Medicine The University of Hong Kong Pokfulam Hong Kong SAR China 4School of Chinese Medicine Faculty of Science The Chinese University of Hong Kong Shatin Hong Kong SAR China and 5Joint Laboratory for Brain Function and Health BFAH Jinan University and The University of Hong Kong Guangzhou China Email Qiuju Yuan - qiujuyuan@ Bing Hu - bhu@ Huanxing Su - hxsu@ Kwok-Fai So - hrmaskf@ Zhixiu Lin - linzx@ Wutian Wu - wtwu@ Corresponding author Open Access Published 25 October 2009 Received 6 July 2009 Journal of Brachial Plexus and Peripheral Nerve Injury 2009 4 18 doi l 749-7221-4-18 Accepted 25 October 2009 This article is available from http content 4 1 18 2009 Yuan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The growth-associated protein GAP-43 plays a crucial role in axonal regeneration in injured neurons. Methods We have used immunohistochemistry to investigate the expression of GAP-43 in spinal motoneurons during nerve reconstruction following root avulsion in the neonatal and adult rats. Results Following the injury GAP-43-immunoreactivity IR

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