Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections: A randomised controlled trial to compare paper-based and web-based modelling experiments | Treweek et al. Implementation Science 2011 6 16 http content 6 1 16 IMPLEMENTATION SCIENCE Implementation Science STUDY PROTOCOL Open Access Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections A randomised controlled trial to compare paper-based and web-based modelling experiments cnA m TrcnA ocilTlan A Piclzcittc2 illi Ai A Prot-idc3 A ortin l-cdcuc4 rioHHio Riondtti5 i lic AA R Dippc5 Shaun liewcck Ian W Ricketts Jillian Francis Martin Eccles Debbie Donetti Nigel D Pitts Graeme MacLennan3 Frank Sullivan 1 Claire Jones2 Mark Weal6 Karen Darnett1 Abstract Background Much implementation research is focused on full-scale trials with little evidence of preceding modelling work. The Medical Research Council Framework for developing and evaluating complex interventions has argued for more and better theoretical and exploratory work prior to a trial as a means of improving intervention development. Intervention modelling experiments IMEs are a way of exploring and refining an intervention before moving to a full-scale trial. They do this by delivering key elements of the intervention in a simulation that approximates clinical practice by for example presenting general practitioners Grs with a clinical scenario about making a treatment decision. Methods The current proposal will run a full web-based IME involving 250 GPs that will advance the methodology of IMEs by directly comparing results with an earlier paper-based IME. Moreover the web-based IME will evaluate an intervention that can be put into a full-scale trial that aims to reduce antibiotic prescribing for upper respiratory tract infections in primary care. The study will also include a trial of email versus postal invitations to participate. Discussion More effective behaviour change interventions are needed and this study will develop one such intervention and a system to model .