Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Reconsidering low-dose aspirin therapy for cardiovascular disease: a study protocol for physician and patient behavioral change | Folks et al. Implementation Science 2011 6 65 http content 6 1 65 Implementation Science IMPLEMENTATION SCIENCE STUDY PROTOCOL Open Access Reconsidering low-dose aspirin therapy for cardiovascular disease a study protocol for physician and patient behavioral change Brittany Folks William G LeBlanc Elizabeth W Staton and Wilson D Pace Abstract Background There are often disparities between current evidence and current practice. Decreasing the gap between desired practice outcomes and observed practice outcomes in the healthcare system is not always easy. Stopping previously recommended or variably recommended interventions may be even harder to achieve than increasing the use of a desired but under-performed activity. For over a decade aspirin has been prescribed for primary prevention of cardiovascular disease and for patients with the coronary artery disease risk equivalents yet there is no substantial evidence of an appropriate risk-benefit ratio to support this practice. This paper describes the protocol of a randomized trial being conducted in six primary care practices in the Denver metropolitan area to examine the effectiveness of three interventional strategies to change physician behavior regarding prescription of low-dose aspirin. Methods All practices received academic detailing one arm received clinician reminders to reconsider aspirin a second arm received both clinician and patient messages to reconsider aspirin. The intervention will run for 15 to 18 months. Data collected at baseline and for outcomes from an electronic health record will be used to assess pre- and post-interventional prescribing as well as to explore any inappropriate decrease in aspirin use by patients with known cardiovascular disease. Discussion This study was designed to investigate effective methods ofchanging physician behavior to decrease the use of aspirin for primary cardiovascular disease prevention. The results of this study will contribute to
