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Immune- and miRNA-response to recombinant interferon beta-1a: A biomarker evaluation study to guide the development of novel type I interferon- based therapies

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The innate immune receptor RIG-I detects viral RNA within the cytosol of infected cells. Activation of RIG-I leads to the induction of antiviral cytokines, in particular type I interferon, the inhibition of a T(H)17 response as well as to the suppression of tumor growth. | Immune- and miRNA-response to recombinant interferon beta-1a: A biomarker evaluation study to guide the development of novel type I interferon- based therapies

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