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Constitutive expression of Bcl-2 induces epithelial-Mesenchymal transition in mammary epithelial cells

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Bcl-2 (B cell lymphoma/leukemia gene-2) is the first proto-oncogene recognized to function by inhibiting programmed cell death/apoptosis. Although much is known about the anti-apoptotic ability of Bcl-2, little information is available concerning its function in other cellular processes, such as cell differentiation. |

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